by 1884, from French mal du sìecle, "world-weariness, atrophy of the spirit, aristocratic boredom, deep melancholy over the condition of the world," supposedly a characteristic condition of young romantics in Europe in the early 19c. It answers to German Weltschmerz.
make-up
makeweight
make-work
mako
mal-
mal du siecle
Malabar
malabsorption
Malachi
malachite
malacia